Home/Past Papers/Sindh / DUHS/Sindh Mdcat Exclusive Course Biology Cell

Sindh Mdcat Exclusive Course Biology Cell — Solved Past Paper with Answers

All 20 MCQs from Sindh Mdcat Exclusive Course Biology Cell, solved with the correct answer highlighted and a full explanation for every question. This is a free MDCAT Sindh / DUHS past paper — no signup, no ads. Practise it interactively in timed mode, drill more with free MDCAT MCQs, or browse all Sindh / DUHS papers.

Attempt this paper interactively →

Q1. In cross-section each Centriole consist of nine (each in triplets) of:

  • A. Microfilaments
  • B. Microvilli
  • C. Microtubules
  • D. Intermediate filaments

Explanation: Typical centrioles are made of 9 triplets of microtubules organized with radial symmetry. Microfilaments, also called actin filaments, are polymers of the protein actin that are part of a cell's cytoskeleton. Microvilli are microscopic cellular membrane protrusions that increase the surface area for diffusion and minimize any increase in volume, and are involved in a wide variety of functions. Intermediate filaments are important components of the cell's cytoskeletal system. They may stabilize organelles, like the nucleus, or they may be involved in specialized junctions. They are distinguished from "thin filaments" by their size (8-10 nm) and the fact that thin filaments are motile.

Q2. The idea that opposed the idea of abiogenesis was proposed by?

  • A. Robert Hooke
  • B. Robert Brown
  • C. Rudolph Virchow
  • D. Lorenz Oken

Explanation: Rudolph Virchow gave statement according to the cell theory that new cells are formed from division of pre-existing cells which opposed the concept of abiogenesis.

Why the other options are wrong
  • A. Robert hook discovered cell.
  • B. Robert brown discovered nucleus.
  • D. Lorenz oken studied the bones, intestines, and umbilical cord, and established basic ideas about elementary units of living organisms, which he called the infusoria.

Q3. Which of the following is NOT a difference that would allow one to distinguish between a prokaryotic and a eukaryotic cell? Presence of absence of the nucleus Presence or absence of the cell wall Membrane bound versus no membrane bound organelles

  • A. I only
  • B. II only
  • C. III only
  • D. I and II only
  • E. I, II and III

Explanation: Eukaryotic cells have nucleus and membrane-bound organelles, which is not the property of prokaryotes.The cell wall is not a distinguishing feature between prokaryotes or eukaryotes.

Why the other options are wrong

    Q4. They serve as a scaffold for formation of higher order chromatin structure:

    • A. Nucleosome
    • B. Nucleus
    • C. Chromosomes
    • D. Histones

    Explanation: Nucleosomes are the basic packing unit of DNA built from histone proteins around which DNA is coiled. Nucleosomes are connected by short DNA segments (termed 'linker DNA') into nucleosomal arrays, which undergo short-range interactions with neighbouring nucleosomes to form chromatin fibres. Subsequent fibre–fibre interactions contribute to the high degree of compaction observed in the condensed chromosome. They serve as a scaffold for formation of higher order chromatin structure as well as for a layer of regulatory control of gene expressio.

    Why the other options are wrong
    • B. This option is incorrect.
    • C. This option is incorrect.
    • D. This option is incorrect.

    Q5. The finger like infoldings, which are formed by inner membrane of mitochondria, are called:

    • A. Ribosomes
    • B. Matrix
    • C. Porin
    • D. Cristae

    Explanation: Factual recall; 'Ribosomes' are organelles, that serve as sites of protein synthesis. 'Matrix' refers to the space confined by the inner mitochondrial membrane within the mitochondria. 'Porin' refers to a transport protein that enables the passive diffusion of certain molecules across a membrane. Cristea are finger-like infoldings, which are formed by the inner membrane of the mitochondria.

    Why the other options are wrong
    • A. Ribosomes are organelles that serve as sites of protein synthesis.
    • B. Matrix refers to the space confined by the inner mitochondrial membrane within the mitochondria.
    • C. 'Porin' refers to a transport protein that enables the passive diffusion of certain molecules across a membrane.

    Q6. Golgi complex is responsible for the formation of secretory granules in _ cell.

    • A. Stomach
    • B. Liver
    • C. Pancreatic
    • D. Muscle

    Explanation: Golgi complex takes part in the formation of secretory vesicles and helps in the transportation of material within or outside the cells. The "β cells" in the pancreatic islets are involved in the storage of insulin secretory granules and instant secretion of insulin.

    Why the other options are wrong
    • A. There are four types of secretory epithelial cells that cover the surface of the stomach.
    • B. Liver, the largest gland in the body itself has secretary functions.
    • D. A band or bundle of fibrous tissue in a human or animal body that has the ability to contract, producing movement in or maintaining the position of parts of the body.

    Q7. All of following are common molecules in membrane of all type of cells except:

    • A. Globular protein
    • B. Cholesterol
    • C. Traces of carbohydrates
    • D. Phospholipid

    Explanation: Globular proteins, polysaccharides and phospholipids are present in both prokaryotic and eukaryotic cell membranes while cholesterol is present only in eukaryotic cell membrane.

    Why the other options are wrong
    • A. Globular proteins, polysaccharides and phospholipids are present in both prokaryotic and eukaryotic cell membranes while cholesterol is present only in eukaryotic cell membrane.
    • C. Globular proteins, polysaccharides and phospholipids are present in both prokaryotic and eukaryotic cell membranes while cholesterol is present only in eukaryotic cell membrane.
    • D. Globular proteins, polysaccharides and phospholipids are present in both prokaryotic and eukaryotic cell membranes while cholesterol is present only in eukaryotic cell membrane.

    Q8. Hydrophobic portion of plasma membrane is present in/at:

    • A. Towards extracellular matrix
    • B. Towards cytoplasm
    • C. Inner core of plasma membrane
    • D. Towards the cytoskeleton

    Explanation: The outside of plasma membrane is surrounded by water molecules. The hydrophobic portions will be present away from water moelcules i.e., towards the inner core of plasma membrane. (Hydrophobic means water-repelling)

    Why the other options are wrong
    • A. The extracellular matrix of plasma membrane is surrounded by water molecules. So, hydrophobic portions will not be present towards extracellular matrix.
    • B. The cyroplasm mainly contains water so hydrophibic portions cannot be present towards cytoplasm.
    • D. Hydrophobic portions are not present towards cytoskeleton.

    Q9. Which of the following statement is incorrect regarding endoplasmic reticulum ?

    • A. Plasma cells have RER in abundance
    • B. RBCs lack both RER and SER
    • C. SER is more than RER in a adipose tissue
    • D. Hepatocytes has both RER and SER
    • E. Non
    Why the other options are wrong
    • A. This statement is correct. The cytoplasm of the plasma cells contains a large amount of Golgi apparatus and rough endoplasmic reticulum. This is in keeping with the primary function of secretion of proteins, and antibodies.
    • B. This statement is correct. Although RBCs are considered cells, they lack a nucleus, nuclear DNA, and most organelles, including the endoplasmic reticulum and mitochondria.
    • C. Adipose tissue is concerned with the conversion, synthesis, and storage of lipids which is why it contains more SER than RER. Since smooth endoplasmic reticulum is concerned with lipid synthesis.
    • D. This statement is correct. Hepatocytes has both RER and SER

    Q10. A function that is related to smooth endoplasmic reticulum:

    • A. Calcium storage
    • B. Steroid synthesis
    • C. Enzyme synthesis
    • D. A and b

    Explanation: Calcium storage and steroid synthesis is the function of SER, while enzyme synthesis is the function of RER. Mechanical support is, however, related to both StR and RER.

    Why the other options are wrong
    • A. The SER plays a crucial role in maintaining calcium homeostasis by acting as a reservoir for calcium ions (Ca2+). It possesses specialized calcium-transporting proteins, such as calcium pumps and channels, which allow for the uptake, release, and sequestration of calcium ions.
    • B. The smooth endoplasmic reticulum (SER) is involved in steroid synthesis within cells.
    • C. Enzyme synthesis does not occur directly in the smooth endoplasmic reticulum (SER). Enzymes are primarily synthesized in the rough endoplasmic reticulum (RER), which is studded with ribosomes responsible for protein synthesis.

    Q11. All of the following organelles contain DNA except:

    • A. Ribosomes
    • B. Chloroplast
    • C. Nucleus
    • D. Mitochondria

    Explanation: Nucleus contains genomic DNA. chloroplast and mitochondria have their own circular genomic DNA while ribosomes are made up of rRNA and protein.

    Why the other options are wrong
    • B. They contain their own DNA and ribosomes.
    • C. It contains its own DNA and ribosomes.
    • D. They contain their own DNA and ribosomes.

    Q12. 40S is the smaller ribosomal subunit associated with:

    • A. E. coli
    • B. C. botulinum
    • C. Yeast
    • D. T. pallidum

    Explanation: E. coli. C. botulinum and T. pallidum are prokaryotic organisms having 30S smaller ribosomal subunit while yeast is eukaryotic organism having 40S smaller ribosomal subunit.

    Why the other options are wrong
    • A. E. coli is prokaryotic organism having 30S smaller ribosomal subunit
    • B. C. botulinum is prokaryotic organism having 30S smaller ribosomal subunit
    • D. T. pallidum is prokaryotic organism having 30S smaller ribosomal subunit

    Q13. Identify the correct pair from the following options:

    • A. DNA replication-Ribosome
    • B. Protein synthesis-SER
    • C. Anaerobic respiration-Cristae
    • D. Modification-Golgi apparatus

    Explanation: DNA replication occurs in nucleus, proteins are synthesized by RER and anaerobic respiration occurs in cytoplasm. Chemical modification of biological molecules is the function of Golgi apparatus.

    Why the other options are wrong
    • A. DNA replication occurs in nucleus.
    • B. Proteins are synthesized by RER.
    • C. Anaerobic respiration occurs in cytoplasm.

    Q14. Modification of proteins and lipids into glycoproteins and glycolipids is the function of:

    • A. Mitochondria
    • B. Rough endoplasmic reticulum
    • C. Smooth endoplasmic reticulum
    • D. Golgi apparatus

    Explanation: The enzymes required for protein glycosylation are solely found in lumen of rough endoplasmic reticulum and Golgi complex. Hence, the more appropriate answer is " D". Golgi bodies are center for modifications and packaging.

    Why the other options are wrong
    • A. It is involved in cellular respiration.
    • B. It is involved in protein synthesis.
    • C. It is involved in synthesis of lipids.

    Q15. The transport of secretory proteins takes place through organelles in which of the following order?

    • A. RER-SER-Golgi apparatus -Secretory vesicles
    • B. SER-RER -Golgi apparatus-Secretory vesicles
    • C. RER-SER-Secretory vesicles-Golgi apparatus
    • D. RER-Golgi apparatus-Secretory vesicles-SER

    Explanation: Proteins are synthesized on RER, and then they are transported in with the help of SER. The modification of these proteins is done in the Golgi complex. Modified proteins are transported out of the cell in the form of secretory vesicles.

    Why the other options are wrong
    • B. Proteins are synthesized on RER, and then they are transported in with the help of SER. The modification of these proteins is done in the Golgi complex. Modified proteins are transported out of the cell in the form of secretory vesicles.
    • C. Proteins are synthesized on RER, and then they are transported in with the help of SER. The modification of these proteins is done in the Golgi complex. Modified proteins are transported out of the cell in the form of secretory vesicles.
    • D. Proteins are synthesized on RER, and then they are transported in with the help of SER. The modification of these proteins is done in the Golgi complex. Modified proteins are transported out of the cell in the form of secretory vesicles.

    Q16. Which of the following organelle is most abundant in those animal com cells which exhibit phagocytic activity?

    • A. Glyoxysomes
    • B. Microbodies
    • C. Lysosomes
    • D. Peroxisomes

    Explanation: Lysosomes are most abundant in those cells which are specialized for phagocytic activities, for example WBCs

    Why the other options are wrong
    • A. Glyoxysomes are found only at seedling stage in oil seed plants.
    • B. Peroxisomes and glyoxysomes are collectively called microbodies.
    • D. They are abundant in liver cells.

    Q17. Strictly speaking, autophagosomes are actually

    • A. Primary lysosomes
    • B. Secondary lysosomes
    • C. Tertiary lysosomes
    • D. None of the above

    Explanation: Autophagosomes are secondary lysosomes which are formed by fusion of primary lysosome with autophagic vesicles. The process is known as autophagocytosis in which unwanted structures within the cell are engulfed. This process occurs during starvation or it occurs in routine to control number of specific organelles.

    Why the other options are wrong
    • A. Autophagosomes are secondary lysosomes which are formed by fusion of primary lysosome with autophagic vesicles. The process is known as autophagocytosis in which unwanted structures within the cell are engulfed. This process occurs during starvation or it occurs in routine to control number of specific organelles.
    • C. Autophagosomes are secondary lysosomes which are formed by fusion of primary lysosome with autophagic vesicles. The process is known as autophagocytosis in which unwanted structures within the cell are engulfed. This process occurs during starvation or it occurs in routine to control number of specific organelles.
    • D. Autophagosomes are secondary lysosomes which are formed by fusion of primary lysosome with autophagic vesicles. The process is known as autophagocytosis in which unwanted structures within the cell are engulfed. This process occurs during starvation or it occurs in routine to control number of specific organelles.

    Q18. It is a disease characterized by the accumulation of lipids in the brain cells leading to:

    • A. Grave's disease
    • B. Addison's disease
    • C. Glycogenosis type Il disease
    • D. Tay-Sachs disease

    Explanation: Storage diseases are due to the absence of lysosomal enzymes. If a lysosomal enzyme responsible for lipid metabolism is absent, it leads to the accumulation of lipids in brain cells which causes mental retardation and death, such storage disease is known as Tay-Sachs disease.

    Why the other options are wrong
    • A. Graves disease is an autoimmune disorder that involves overactivity of the thyroid (hyperthyroidism).
    • B. In Addison's disease, the adrenal glands make too little cortisol and, often, too little of another hormone, aldosterone.
    • C. In glycogenosis type II disease, the liver and muscle appear illed with glycogen within membrane bound organelles. In this disease, an enzyme that degrades glycogen to glucose, is absent.

    Q19. What is the specific name given to the biological membrane that surrounds the vacuoles?

    • A. Plasma membrane
    • B. Endomembrane
    • C. Plasmalemma
    • D. Tonoplast

    Explanation: Vacuole is single membrane bounded organelle. This single membrane around vacuole is known as tonoplast.

    Why the other options are wrong
    • A. It surrounds the cell.
    • B. The endomembrane system (endo- = “within”) is a group of membranes and organelles in eukaryotic cells that works together to modify, package, and transport lipids and proteins.
    • C. Cell membrane which surrounds the cell is also called plasmalemma.

    Q20. Which of the following proteins is present in microtubules?

    • A. Tubulin
    • B. Myosin
    • C. Actin
    • D. Tropomyosin

    Explanation: Tubulin is the most abundant protein found in microtubules while myosin, actin and tropomyosin are found in microfilaments.

    Why the other options are wrong
    • B. It is found in thin myofilaments.
    • C. It is found in microfilaments.
    • D. It is found in microfilaments.

    More Sindh / DUHS Solved Papers